Designing chimeric enzymes inspired by fungal cellulosomes
Cellulosomes are synthesized by anaerobic bacteria and fungi to degrade lignocellulose via synergistic action of multiple enzymes fused to a protein scaffold. Through templating key protein domains (cohesin and dockerin), designer cellulosomes have been engineered from bacterial motifs to alter the...
Main Authors: | Sean P. Gilmore, Stephen P. Lillington, Charles H. Haitjema, Randall de Groot, Michelle A. O'Malley |
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Format: | Article |
Language: | English |
Published: |
KeAi Communications Co., Ltd.
2020-03-01
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Series: | Synthetic and Systems Biotechnology |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2405805X2030003X |
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