Runx2 transcriptome of prostate cancer cells: insights into invasiveness and bone metastasis

<p>Abstract</p> <p>Background</p> <p>Prostate cancer (PCa) cells preferentially metastasize to bone at least in part by acquiring osteomimetic properties. Runx2, an osteoblast master transcription factor, is aberrantly expressed in PCa cells, and promotes their metastat...

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Bibliographic Details
Main Authors: Gabet Yankel, Khalid Omar, Baniwal Sanjeev K, Shah Ruchir R, Purcell Daniel J, Mav Deepak, Kohn-Gabet Alice E, Shi Yunfan, Coetzee Gerhard A, Frenkel Baruch
Format: Article
Language:English
Published: BMC 2010-09-01
Series:Molecular Cancer
Online Access:http://www.molecular-cancer.com/content/9/1/258