All-trans retinoic acid attenuates the progression of Ang II-induced abdominal aortic aneurysms in ApoE−/−mice

All-trans retinoic acid attenuates the progression of Ang II-induced abdominal aortic aneurysms in ApoE−/−mice

Abstract Background To determine whether all-trans retinoic acid (ATRA) can influence the development of Angiotensin II (Ang II) induced experimental abdominal aortic aneurysms (AAAs). Methods Apolipoprotein E knock-out (ApoE−/−) mice were randomly assigned to 4 groups. Mice in the AAA and ATRA grou...

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Bibliographic Details
Main Authors: Jie Xiao, Jinping Liu, Iohang Lio, Chuanlei Yang, Xing Chen, Hua Zhang, Shuxia Wang, Zhanjie Wei
Format: Article
Language:English
Published: BMC 2020-07-01
Series:Journal of Cardiothoracic Surgery
Subjects:
Abdominal aortic aneurysm
All-trans retinoic acid (ATRA)
Inflammation
Online Access:http://link.springer.com/article/10.1186/s13019-020-01208-w

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