Acquired Hemophilia A with a Rare Presentation of Acute Subdural Hematoma

Acquired Hemophilia A with a Rare Presentation of Acute Subdural Hematoma

An 80-year-old man was admitted for acute subdural hematoma caused by a mild brain injury. His coagulation test showed an isolated prolongation of activated partial thromboplastin time (aPTT). Though the subdural hematoma did not progress, oozing bleed from the wound of tracheostomy continued. Failu...

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Main Authors: Yoshihide Sehara, Yuka Hayashi, Jun Mimuro
Format: Article
Language:English
Published: Hindawi Limited 2015-01-01
Series:Case Reports in Neurological Medicine
Online Access:http://dx.doi.org/10.1155/2015/543927
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spelling doaj-7a3b481290f141e988c0be9c51d5d2a72020-11-24T21:04:24ZengHindawi LimitedCase Reports in Neurological Medicine2090-66682090-66762015-01-01201510.1155/2015/543927543927Acquired Hemophilia A with a Rare Presentation of Acute Subdural HematomaYoshihide Sehara0Yuka Hayashi1Jun Mimuro2Department of Neurology, Ishibashi General Hospital, Shimotsuke 329-0596, JapanDepartment of Neurology, Ishibashi General Hospital, Shimotsuke 329-0596, JapanDepartment of Hematology, Ishibashi General Hospital, Shimotsuke 329-0596, JapanAn 80-year-old man was admitted for acute subdural hematoma caused by a mild brain injury. His coagulation test showed an isolated prolongation of activated partial thromboplastin time (aPTT). Though the subdural hematoma did not progress, oozing bleed from the wound of tracheostomy continued. Failure of correction on aPTT mixing test supported the presence of an inhibitor to a coagulation factor. Once the diagnosis of acquired hemophilia A (AHA) was made, steroid therapy was performed, which leads him to complete remission of AHA. Isolated prolongation of aPTT can be the key to diagnose a rare coagulopathy, such as AHA.http://dx.doi.org/10.1155/2015/543927
collection DOAJ
language English
format Article
sources DOAJ
author Yoshihide Sehara
Yuka Hayashi
Jun Mimuro
spellingShingle Yoshihide Sehara
Yuka Hayashi
Jun Mimuro
Acquired Hemophilia A with a Rare Presentation of Acute Subdural Hematoma
Case Reports in Neurological Medicine
author_facet Yoshihide Sehara
Yuka Hayashi
Jun Mimuro
author_sort Yoshihide Sehara
title Acquired Hemophilia A with a Rare Presentation of Acute Subdural Hematoma
title_short Acquired Hemophilia A with a Rare Presentation of Acute Subdural Hematoma
title_full Acquired Hemophilia A with a Rare Presentation of Acute Subdural Hematoma
title_fullStr Acquired Hemophilia A with a Rare Presentation of Acute Subdural Hematoma
title_full_unstemmed Acquired Hemophilia A with a Rare Presentation of Acute Subdural Hematoma
title_sort acquired hemophilia a with a rare presentation of acute subdural hematoma
publisher Hindawi Limited
series Case Reports in Neurological Medicine
issn 2090-6668
2090-6676
publishDate 2015-01-01
description An 80-year-old man was admitted for acute subdural hematoma caused by a mild brain injury. His coagulation test showed an isolated prolongation of activated partial thromboplastin time (aPTT). Though the subdural hematoma did not progress, oozing bleed from the wound of tracheostomy continued. Failure of correction on aPTT mixing test supported the presence of an inhibitor to a coagulation factor. Once the diagnosis of acquired hemophilia A (AHA) was made, steroid therapy was performed, which leads him to complete remission of AHA. Isolated prolongation of aPTT can be the key to diagnose a rare coagulopathy, such as AHA.
url http://dx.doi.org/10.1155/2015/543927
work_keys_str_mv AT yoshihidesehara acquiredhemophiliaawithararepresentationofacutesubduralhematoma
AT yukahayashi acquiredhemophiliaawithararepresentationofacutesubduralhematoma
AT junmimuro acquiredhemophiliaawithararepresentationofacutesubduralhematoma
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