Performance of CURB-65, PSI, and APACHE-II for predicting COVID-19 pneumonia severity and mortality

• Main Authors: Junnian Chen, Bang Liu, Houwei Du, Hailong Lin, Cunrong Chen, Shanshan Rao, Ranjie Yu, Jingjing Wang, Zhiqiang Xue, Yixian Zhang, Yanghuang Xie
• Format: Article
• Language: English
• Published: SAGE Publishing 2021-07-01
• Series: European Journal of Inflammation
• Online Access: https://doi.org/10.1177/20587392211027083

No prognostic tools for the prediction of COVID-19 pneumonia severity and mortality are available. We explored whether CURB-65, PSI, and APACHE-II could predict COVID-19 pneumonia severity and mortality. We included 167 patients with confirmed COVID-19 pneumonia in this retrospective study. The severity and 30-day mortality of COVID-19 pneumonia were predicted using PSI, CURB-65, and APACHE-II scales. Kappa test was performed to compare the consistency of the three scales. There was a significant difference in the distribution of the scores of the three scales ( P  < 0.001). Patients with PSI class ⩽III, CURB-65 ⩽1, and APACHE-II-I all survived. The ROC analysis showed the areas under the curve of the PSI, CURB-65, and APACHE-II scales were 0.83 (95% CI, 0.74–0.93), 0.80 (95% CI, 0.69–0.90), and 0.83 (95% CI, 0.75–0.92), respectively. Our findings suggest that PSI and CURB-65 might be useful to predict the severity and mortality of COVID-19 pneumonia.