Adsorption of Phenazines Produced by <i>Pseudomonas aeruginosa</i> Using AST-120 Decreases Pyocyanin-Associated Cytotoxicity

Adsorption of Phenazines Produced by <i>Pseudomonas aeruginosa</i> Using AST-120 Decreases Pyocyanin-Associated Cytotoxicity

AST-120 (Kremezin) is used to treat progressive chronic kidney disease by adsorbing uremic toxin precursors produced by the gut microbiota, such as indole and phenols. Previously, we found that AST-120 decreased drug tolerance and virulence in <i>Escherichia coli</i> by adsorbing indole....

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Bibliographic Details
Main Authors: Hidetada Hirakawa, Ayako Takita, Motoyuki Uchida, Yuka Kaneko, Yuto Kakishima, Koichi Tanimoto, Wataru Kamitani, Haruyoshi Tomita
Format: Article
Language:English
Published: MDPI AG 2021-04-01
Series:Antibiotics
Subjects:
antimicrobial resistance (AMR)
multi-drug resistance (MDR)
quorum Sensing
virulence
bacterial pathogenesis
molecular genetics
Online Access:https://www.mdpi.com/2079-6382/10/4/434

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https://www.mdpi.com/2079-6382/10/4/434

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