Lysosomal Storage Diseases-Regulating Neurodegeneration

Autophagy is a complex pathway regulated by numerous signaling events that recycles macromolecules and can be perturbed in lysosomal storage diseases (LSDs). The concept of LSDs, which are characterized by aberrant, excessive storage of cellular material in lysosomes, developed following the discove...

Full description

Bibliographic Details
Main Authors: Rob U. Onyenwoke, Jay E. Brenman
Format: Article
Language:English
Published: SAGE Publishing 2015-01-01
Series:Journal of Experimental Neuroscience
Online Access:https://doi.org/10.4137/JEN.S25475