Common anti-oxidant vitamin C as an anti-infective agent with remedial role on SARS-CoV-2 infection. An update

• Main Authors: Christos Michailides, Dimitrios Velissaris
• Format: Article
• Language: English
• Published: PAGEPress Publications 2021-07-01
• Series: Monaldi Archives for Chest Disease
• Subjects: SARS-CoV-2 infection, Vitamin C, COVID-19 treatment
• Online Access: https://monaldi-archives.org/index.php/macd/article/view/1808

Coronavirus disease -2019 (COVID-19) has led to a worldwide multifaceted crisis. The medical world agonizes to contend with the problem, but a string of tested medications has been proven unavailing. Vitamin C is well described as a salutary antioxidant and some trials conclude that it may be a potential antiviral drug. In high doses, Vitamin C can alternate crucial steps in the pathogenesis of sepsis and acute respiratory distress syndrome. This dynamic was the driving force behind trials around the world that tried immunonutrition as a weapon against clinical entities. We summarize the mechanisms of action of Vitamin C and its role against infections and the current literature referring to the potential role of Vitamin C in SARS-CoV-2 infection, also as a contingent treatment agent.