Site-1 protease regulates skeletal stem cell population and osteogenic differentiation in mice
Site-1 protease (S1P) is a proprotein convertase with essential functions in the conversion of precursor proteins to their active form. In earlier studies, we demonstrated that S1P ablation in the chondrocyte lineage results in a drastic reduction in endochondral bone formation. To investigate the m...
Main Authors: | Debabrata Patra, Elizabeth DeLassus, Jennifer Mueller, Grazia Abou-Ezzi, Linda J. Sandell |
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Format: | Article |
Language: | English |
Published: |
The Company of Biologists
2018-02-01
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Series: | Biology Open |
Subjects: | |
Online Access: | http://bio.biologists.org/content/7/2/bio032094 |
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