Loss-of-Function Variants in Cytoskeletal Genes Are Associated with Early-Onset Atrial Fibrillation

Loss-of-Function Variants in Cytoskeletal Genes Are Associated with Early-Onset Atrial Fibrillation

Atrial fibrillation (AF) is the most common cardiac arrhythmia, and it is associated with an increased risk of heart failure, stroke, dementia, and death. Recently, titin-truncating variants (TTNtv), which are predominantly associated with dilated cardiomyopathy (DCM), were associated with early-ons...

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Bibliographic Details
Main Authors: Oliver Bundgaard Vad, Christian Paludan-Müller, Gustav Ahlberg, Silje Madeleine Kalstø, Jonas Ghouse, Laura Andreasen, Stig Haunsø, Arnljot Tveit, Ahmad Sajadieh, Ingrid Elisabeth Christophersen, Jesper Hastrup Svendsen, Morten Salling Olesen
Format: Article
Language:English
Published: MDPI AG 2020-01-01
Series:Journal of Clinical Medicine
Subjects:
atrial fibrillation
genetics
arrhythmia
cardiology
next-generation sequencing
cardiomyopathy
Online Access:https://www.mdpi.com/2077-0383/9/2/372

Internet

https://www.mdpi.com/2077-0383/9/2/372

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