NRAS Mutations May Be Involved in the Pathogenesis of Cutaneous Rosai Dorfman Disease: A Pilot Study

NRAS Mutations May Be Involved in the Pathogenesis of Cutaneous Rosai Dorfman Disease: A Pilot Study

Background: Purely cutaneous Rosai-Dorfman disease (RDD) is a rare histiocytic proliferative disorder limited to the skin. To date, its pathogenesis remains unclear. Owing to recent findings of specific mutations in the mitogen-activated protein kinase/extracellular signal-regulated kinase (MAPK/ERK...

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Bibliographic Details
Main Authors: Kuan-Jou Wu, Shu-Hao Li, Jia-Bin Liao, Chien-Chun Chiou, Chieh-Shan Wu, Chien-Chin Chen
Format: Article
Language:English
Published: MDPI AG 2021-05-01
Series:Biology
Subjects:
skin
Rosai–Dorfman
genetic
KRAS
NRAS
BRAF
Online Access:https://www.mdpi.com/2079-7737/10/5/396

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