Pd-catalysed ligand-enabled carboxylate-directed highly regioselective arylation of aliphatic acids
Palladium catalysed C-H functionalization ofsp3carbons typically requires the installation and subsequent removal of a temporary directing group. Here the authors report a method allowing C-H functionalization in carboxylic acids in which the carboxylate acts as a directing group.
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Publishing Group
2017-04-01
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| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/ncomms14904 |