Non Classical HLA Genes and Non-HLA Genes in a Population of Infants at Familial Risk of Atopy

Non Classical HLA Genes and Non-HLA Genes in a Population of Infants at Familial Risk of Atopy

Aim: We investigated on parental history and IgE serum level in 2588 consecutive newborns to individuate babies “at risk” of atopy at birth and we analysed the polymorphisms of class III region to evaluate the association with immunogenetic markers of HLA: C4A, C4B, LTA, RAGE and TNFA genes; we perf...

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Bibliographic Details
Main Authors: A. De Silvestri, C. Belloni, M. De Amici, P. Mazzola, M. Zorzetto, M. Martinetti, L. Salvaneschi, M. Cuccia
Format: Article
Language:English
Published: Hindawi Limited 2006-01-01
Series:Disease Markers
Online Access:http://dx.doi.org/10.1155/2006/321798
Description
Summary:Aim: We investigated on parental history and IgE serum level in 2588 consecutive newborns to individuate babies “at risk” of atopy at birth and we analysed the polymorphisms of class III region to evaluate the association with immunogenetic markers of HLA: C4A, C4B, LTA, RAGE and TNFA genes; we performed TNF and IgE receptor (FCERB1) physiologically related gene polymorphisms.
ISSN:0278-0240
1875-8630

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