The five dimensions of receptor pharmacology exemplified by melatonin receptors: An opinion
Abstract Receptology has been complicated with enhancements in our knowledge of G‐protein‐coupled‐receptor (GPCR) biochemistry. This complexity is exemplified by the pharmacology of melatonin receptors. Here, we describe the complexity of GPCR biochemistry in five dimensions: (a) receptor expression...
Main Authors: | Jean A. Boutin, Céline Legros |
---|---|
Format: | Article |
Language: | English |
Published: |
Wiley
2020-02-01
|
Series: | Pharmacology Research & Perspectives |
Subjects: | |
Online Access: | https://doi.org/10.1002/prp2.556 |
Similar Items
-
Identification of agonists for a group of human odorant receptors
by: Daniela eGonzalez-Kristeller, et al.
Published: (2015-03-01) -
Structural insight into the activation of a class B G-protein-coupled receptor by peptide hormones in live human cells
by: Lisa Seidel, et al.
Published: (2017-08-01) -
β-Arrestin Based Receptor Signaling Paradigms: Potential Therapeutic Targets for Complex Age-Related Disorders
by: Jaana van Gastel, et al.
Published: (2018-11-01) -
Characterization of the various functional pathways elicited by synthetic agonists or antagonists at the melatonin MT1 and MT2 receptors
by: Céline Legros, et al.
Published: (2020-02-01) -
Structure-based discovery of potent and selective melatonin receptor agonists
by: Nilkanth Patel, et al.
Published: (2020-03-01)