Stereoselective Synthesis of Southern Fragment of Hantupeptin-A

Stereoselective Synthesis of Southern Fragment of Hantupeptin-A

The stereo selective synthesis of the southern fragment (C21-C41) of Hantupeptin–A is described. The required stereochemistry of b-hydroxy-a-methyl acid unit was accomplished through Aldol reaction using Evan’s chiral auxiliary followed by the installation of terminal alkyne with Ohira–Bestmann reag...

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Bibliographic Details
Main Authors: Sri Nivas Avula, Malladi Sunitha, Rao Govind Chakunta
Format: Article
Language:English
Published: Slovenian Chemical Society 2016-05-01
Series:Acta Chimica Slovenica
Subjects:
Hantupeptin A
Aldol Reaction
Stereoselective synthesis
Peptide
Evan’s auxiliary
Online Access:https://journals.matheo.si/index.php/ACSi/article/view/2322

Internet

https://journals.matheo.si/index.php/ACSi/article/view/2322

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