Macrophage Activation Syndrome as Onset of Systemic Lupus Erythematosus: A Case Report and a Review of the Literature
Macrophage activation syndrome (MAS) is a potentially fatal condition. It belongs to the hemophagocytic lymphohistiocytosis group of diseases. In adults, MAS is rarely associated with systemic lupus erythematosus, but it also arises as complication of several systemic autoimmune disorders, like anky...
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doaj-79c34bd25706452cbdf1b6a0242432ee2020-11-25T00:04:50ZengHindawi LimitedCase Reports in Medicine1687-96271687-96352015-01-01201510.1155/2015/294041294041Macrophage Activation Syndrome as Onset of Systemic Lupus Erythematosus: A Case Report and a Review of the LiteratureGuido Granata0Dario Didona1Giuseppina Stifano2Aldo Feola3Massimo Granata4UOC Immunologia Clinica A, Dipartimento di Medicina Clinica, Policlinico Umberto I, Sapienza Università di Roma, 00185 Roma, ItalyI Divisione Dermatologica, Istituto Dermopatico dell’Immacolata IRCCS, 00167 Roma, ItalyUOC Immunologia Clinica A, Dipartimento di Medicina Clinica, Policlinico Umberto I, Sapienza Università di Roma, 00185 Roma, ItalyUOC Immunologia Clinica A, Dipartimento di Medicina Clinica, Policlinico Umberto I, Sapienza Università di Roma, 00185 Roma, ItalyUOC Immunologia Clinica A, Dipartimento di Medicina Clinica, Policlinico Umberto I, Sapienza Università di Roma, 00185 Roma, ItalyMacrophage activation syndrome (MAS) is a potentially fatal condition. It belongs to the hemophagocytic lymphohistiocytosis group of diseases. In adults, MAS is rarely associated with systemic lupus erythematosus, but it also arises as complication of several systemic autoimmune disorders, like ankylosing spondylitis, rheumatoid arthritis, and adult-onset Still’s disease. Several treatment options for MAS have been reported in the literature, including a therapeutic regimen of etoposide, dexamethasone, and cyclosporine. Here we report a case of 42-year-old woman in whom MAS occurred as onset of systemic lupus erythematosus.http://dx.doi.org/10.1155/2015/294041 |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Guido Granata Dario Didona Giuseppina Stifano Aldo Feola Massimo Granata |
spellingShingle |
Guido Granata Dario Didona Giuseppina Stifano Aldo Feola Massimo Granata Macrophage Activation Syndrome as Onset of Systemic Lupus Erythematosus: A Case Report and a Review of the Literature Case Reports in Medicine |
author_facet |
Guido Granata Dario Didona Giuseppina Stifano Aldo Feola Massimo Granata |
author_sort |
Guido Granata |
title |
Macrophage Activation Syndrome as Onset of Systemic Lupus Erythematosus: A Case Report and a Review of the Literature |
title_short |
Macrophage Activation Syndrome as Onset of Systemic Lupus Erythematosus: A Case Report and a Review of the Literature |
title_full |
Macrophage Activation Syndrome as Onset of Systemic Lupus Erythematosus: A Case Report and a Review of the Literature |
title_fullStr |
Macrophage Activation Syndrome as Onset of Systemic Lupus Erythematosus: A Case Report and a Review of the Literature |
title_full_unstemmed |
Macrophage Activation Syndrome as Onset of Systemic Lupus Erythematosus: A Case Report and a Review of the Literature |
title_sort |
macrophage activation syndrome as onset of systemic lupus erythematosus: a case report and a review of the literature |
publisher |
Hindawi Limited |
series |
Case Reports in Medicine |
issn |
1687-9627 1687-9635 |
publishDate |
2015-01-01 |
description |
Macrophage activation syndrome (MAS) is a potentially fatal condition. It belongs to the hemophagocytic lymphohistiocytosis group of diseases. In adults, MAS is rarely associated with systemic lupus erythematosus, but it also arises as complication of several systemic autoimmune disorders, like ankylosing spondylitis, rheumatoid arthritis, and adult-onset Still’s disease. Several treatment options for MAS have been reported in the literature, including a therapeutic regimen of etoposide, dexamethasone, and cyclosporine. Here we report a case of 42-year-old woman in whom MAS occurred as onset of systemic lupus erythematosus. |
url |
http://dx.doi.org/10.1155/2015/294041 |
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