Infantile hemangiomas: An update on pathogenesis, associations, and management

• Main Authors: Karina L Vivar, Anthony J Mancini
• Format: Article
• Language: English
• Published: Wolters Kluwer Medknow Publications 2018-01-01
• Series: Indian Journal of Paediatric Dermatology
• Subjects: Infantile hemangioma; propranolol; timolol; vascular
• Online Access: http://www.ijpd.in/article.asp?issn=2319-7250;year=2018;volume=19;issue=4;spage=293;epage=303;aulast=Vivar

Infantile hemangiomas (IH) are the most common vascular neoplasm in infants. The typical clinical course of IH follows a pattern of growth (proliferation) followed by spontaneous involution. The majority of IH are isolated to the skin; however, some cutaneous IH can be associated with internal organ involvement or anomalies. IH which are functionally impairing, ulcerated or potentially disfiguring require therapy. Treatment options include systemic or topical beta-blockers, systemic or intralesional corticosteroids, pulsed dye laser therapy, or surgical excision. In this article, we review the updated understanding of IH pathogenesis, clinical presentations and associations, and approaches to management.