Sex differences in microRNA-mRNA networks: examination of novel epigenetic programming mechanisms in the sexually dimorphic neonatal hypothalamus
Abstract Background Sexual differentiation of the male brain, and specifically the stress circuitry in the hypothalamus, is primarily driven by estrogen exposure during the perinatal period. Surprisingly, this single hormone promotes diverse programs of sex-specific development that vary widely betw...
Main Authors: | Christopher P. Morgan, Tracy L. Bale |
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Format: | Article |
Language: | English |
Published: |
BMC
2017-08-01
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Series: | Biology of Sex Differences |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s13293-017-0149-3 |
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