Real time measures of prestin charge and fluorescence during plasma membrane trafficking reveal sub-tetrameric activity.

Real time measures of prestin charge and fluorescence during plasma membrane trafficking reveal sub-tetrameric activity.

Prestin (SLC26a5) is the outer hair cell integral membrane motor protein that drives cochlear amplification, and has been described as an obligate tetramer. We studied in real time the delivery of YFP-prestin to the plasma membrane of cells from a tetracycline-inducible cell line. Following the rele...

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Bibliographic Details
Main Authors: Shumin Bian, Dhasakumar Navaratnam, Joseph Santos-Sacchi
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3677934?pdf=render

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