The Performance of HepG2 and HepaRG Systems through the Glass of Acetaminophen-Induced Toxicity

Investigation of drug-induced liver injuries requires appropriate in vivo and in vitro toxicological model systems. In our study, an attempt was made to compare the hepatocarcinoma HepG2 and the stem cell-derived HepaRG cell lines both in two- and three-dimensional culture conditions to find the mos...

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Bibliographic Details
Main Authors: Tamás Lőrincz, Veronika Deák, Kinga Makk-Merczel, Dóra Varga, Péter Hajdinák, András Szarka
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Series:Life
Subjects:
Online Access:https://www.mdpi.com/2075-1729/11/8/856