Region-Specific Reduction of BDNF Protein and Transcripts in the Hippocampus of Juvenile Rats Prenatally Treated With Sodium Valproate

Region-Specific Reduction of BDNF Protein and Transcripts in the Hippocampus of Juvenile Rats Prenatally Treated With Sodium Valproate

Autism is a neurodevelopmental disorder characterized by a deep deficit in language and social interaction, accompanied by restricted, stereotyped and repetitive behaviors. The use of genetic autism animal models has revealed that the alteration of the mechanisms controlling the formation and matura...

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Bibliographic Details
Main Authors: Constanza R. Fuentealba, Jenny L. Fiedler, Francisco A. Peralta, Ana María Avalos, Felipe I. Aguayo, Katherine P. Morgado-Gallardo, Esteban E. Aliaga
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-11-01
Series:Frontiers in Molecular Neuroscience
Subjects:
autism
valproate
BDNF
long-3′UTR-bdnf
hippocampus
Online Access:https://www.frontiersin.org/article/10.3389/fnmol.2019.00261/full

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