Transcriptomic analysis reveals differential gene expression, alternative splicing, and novel exons during mouse trophoblast stem cell differentiation

Transcriptomic analysis reveals differential gene expression, alternative splicing, and novel exons during mouse trophoblast stem cell differentiation

Abstract Background Differentiation of mouse trophoblast stem cells (TSCs) to trophoblast giant cells (TGCs) has been widely used as a model system to study placental development and function. While several differentially expressed genes, including regulators of TSC differentiation, have been identi...

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Bibliographic Details
Main Authors: Rahim Ullah, Ambreen Naz, Hafiza Sara Akram, Zakir Ullah, Muhammad Tariq, Aziz Mithani, Amir Faisal
Format: Article
Language:English
Published: BMC 2020-08-01
Series:Stem Cell Research & Therapy
Subjects:
Trophoblast stem cells
Trophoblast giant cells
Placental development
RNA-seq
Stem cell differentiation
Alternative splicing
Online Access:http://link.springer.com/article/10.1186/s13287-020-01848-8

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