The Metabolic Stability of the Nicotinic Acetylcholine Receptor at the Neuromuscular Junction

The Metabolic Stability of the Nicotinic Acetylcholine Receptor at the Neuromuscular Junction

The clustering and maintenance of nicotinic acetylcholine receptors (AChRs) at high density in the postsynaptic membrane is a hallmark of the mammalian neuromuscular junction (NMJ). The regulation of receptor density/turnover rate at synapses is one of the main thrusts of neurobiology because it pla...

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Bibliographic Details
Main Authors: Isabel Martinez-Pena y Valenzuela, Mohammed Akaaboune
Format: Article
Language:English
Published: MDPI AG 2021-02-01
Series:Cells
Subjects:
AChR
metabolic stability
synaptic activity
denervation
endocytosis
recycling
Online Access:https://www.mdpi.com/2073-4409/10/2/358

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