RT-SHIV, an infectious CCR5-tropic chimeric virus suitable for evaluating HIV reverse transcriptase inhibitors in macaque models
<p>Abstract</p> <p>Background</p> <p>Non-nucleoside reverse transcriptase inhibitors (NNRTIs) are an important category of drugs for both chemotherapy and prevention of human immunodeficiency virus type 1 (HIV-1) infection. However, current non-human primate (NHP) model...
Main Authors: | Emau Peter, Agy Michael B, Saifuddin Mohammed, Tian Baoping, Jiang Yonghou, Cairns J Scott, Tsai Che-Chung |
---|---|
Format: | Article |
Language: | English |
Published: |
BMC
2009-11-01
|
Series: | AIDS Research and Therapy |
Online Access: | http://www.aidsrestherapy.com/content/6/1/23 |
Similar Items
-
RT-SHIV subpopulation dynamics in infected macaques during anti-HIV therapy
by: KewalRamani Vineet N, et al.
Published: (2009-11-01) -
Antibody-based CCR5 blockade protects Macaques from mucosal SHIV transmission
by: Xiao L. Chang, et al.
Published: (2021-06-01) -
Variation of human immunodeficiency virus type-1 reverse transcriptase within the simian immunodeficiency virus genome of RT-SHIV.
by: Debra A Wadford, et al.
Published: (2014-01-01) -
A MIV-150/zinc acetate gel inhibits SHIV-RT infection in macaque vaginal explants.
by: Patrick Barnable, et al.
Published: (2014-01-01) -
Generation of a neutralization-resistant CCR5 tropic SHIV-MK38 molecular clone, a derivative of SHIV-89.6
by: Ishida, Yuki
Published: (2016)