Caffeine as A Catalyst for A Four-Component Synthesis of Dihydropyrano [2, 3-C]Pyrazoles in Water
We describe a one-pot four component synthesis of pyrano[2,3-c]pyrazoles from hydrazine hydrate or phenyl hydrazine, ethyl acetoacetate, an aldehyde, and malononitrile in the presence of catalytic amounts of a caffeine as a green catalyst in water at 50 ºC. The present protocol offers the advantage...
| Main Authors: | , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
PURKH
2019-04-01
|
| Series: | To Chemistry Journal |
| Subjects: | |
| Online Access: | https://www.purkh.com/index.php/tochem/article/view/372 |