Topical HPMC/S-Nitrosoglutathione Solution Decreases Inflammation and Bone Resorption in Experimental Periodontal Disease in Rats.

Topical HPMC/S-Nitrosoglutathione Solution Decreases Inflammation and Bone Resorption in Experimental Periodontal Disease in Rats.

S-nitrosoglutathione (GSNO) is a nitric oxide (NO) donor, which exerts antioxidant, anti-inflammatory, and microbicidal actions. Intragingival application of GSNO was already shown to decrease alveolar bone loss, inflammation and oxidative stress in an experimental periodontal disease (EPD) model. I...

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Main Authors: Conceição S Martins, Renata F C Leitão, Deiziane V S Costa, Iracema M Melo, Glaylton S Santos, Vilma Lima, Victor Baldim, Deysi V T Wong, Luana E Bonfim, Cíntia B Melo, Marcelo G de Oliveira, Gerly A C Brito
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4846037?pdf=render

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