Methionine sulfoxide reductase B3 deficiency inhibits the development of diet-induced insulin resistance in mice

Methionine sulfoxide reductase B3 deficiency inhibits the development of diet-induced insulin resistance in mice

Oxidative and endoplasmic reticulum (ER) stress are involved in mediating high-fat diet (HFD)-induced insulin resistance. As the ER-localized methionine sulfoxide reductase B3 (MsrB3) protects cells against oxidative and ER stress, we hypothesized that MsrB3 might be associated with HFD-induced insu...

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Bibliographic Details
Main Authors: Hye-Na Cha, Chang-Hoon Woo, Hwa-Young Kim, So-Young Park
Format: Article
Language:English
Published: Elsevier 2021-01-01
Series:Redox Biology
Subjects:
Methionine sulfoxide reductase B3
Insulin resistance
High-fat diet
Oxidative stress
Unfolded protein response
Mitochondrial oxidative phosphorylation
Online Access:http://www.sciencedirect.com/science/article/pii/S2213231720310284

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http://www.sciencedirect.com/science/article/pii/S2213231720310284

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