Concurrent Chemoradiation in Anal Cancer Patients Delivered with Bone Marrow-Sparing IMRT: Final Results of a Prospective Phase II Trial

Concurrent Chemoradiation in Anal Cancer Patients Delivered with Bone Marrow-Sparing IMRT: Final Results of a Prospective Phase II Trial

We investigated the role of the selective avoidance of haematopoietically active pelvic bone marrow (BM), with a targeted intensity-modulated radiotherapy (IMRT) approach, to reduce acute hematologic toxicity (HT) in anal cancer patients undergoing concurrent chemo-radiation. We designed a one-armed...

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Bibliographic Details
Main Authors: Francesca Arcadipane, Patrick Silvetti, Francesco Olivero, Alessio Gastino, Roberta Carlevato, Ilaria Chiovatero, Lavinia Spinelli, Massimiliano Mistrangelo, Paola Cassoni, Giuliana Ritorto, Elena Gallio, Adriana Lesca, Riccardo Faletti, Francesca Romana Giglioli, Christian Fiandra, Umberto Ricardi, Pierfrancesco Franco
Format: Article
Language:English
Published: MDPI AG 2021-05-01
Series:Journal of Personalized Medicine
Subjects:
anal cancer
bone marrow-sparing IMRT
hematologic toxicity
radiotherapy
Online Access:https://www.mdpi.com/2075-4426/11/5/427

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