XIAP is not required for human tumor cell survival in the absence of an exogenous death signal
<p>Abstract</p> <p>Background</p> <p>The X-linked Inhibitor of Apoptosis (XIAP) has attracted much attention as a cancer drug target. It is the only member of the IAP family that can directly inhibit caspase activity <it>in vitro</it>, and it can regulate ap...
Main Authors: | Peach Robert, Scott Fiona L, Sensintaffar John, Hager Jeffrey H |
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Format: | Article |
Language: | English |
Published: |
BMC
2010-01-01
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Series: | BMC Cancer |
Online Access: | http://www.biomedcentral.com/1471-2407/10/11 |
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