XIAP is not required for human tumor cell survival in the absence of an exogenous death signal

<p>Abstract</p> <p>Background</p> <p>The X-linked Inhibitor of Apoptosis (XIAP) has attracted much attention as a cancer drug target. It is the only member of the IAP family that can directly inhibit caspase activity <it>in vitro</it>, and it can regulate ap...

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Bibliographic Details
Main Authors: Peach Robert, Scott Fiona L, Sensintaffar John, Hager Jeffrey H
Format: Article
Language:English
Published: BMC 2010-01-01
Series:BMC Cancer
Online Access:http://www.biomedcentral.com/1471-2407/10/11