A New Look into the Mode of Action of Metal-Based Anticancer Drugs

A New Look into the Mode of Action of Metal-Based Anticancer Drugs

The mode of action of Pt- and Pd-based anticancer agents (cisplatin and Pd<sub>2</sub>Spm) was studied by characterising their impact on DNA. Changes in conformation and mobility at the molecular level in hydrated DNA were analysed by quasi-elastic and inelastic neutron scattering techni...

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Bibliographic Details
Main Authors: M. Paula M. Marques, Ana L. M. Batista de Carvalho, Adriana P. Mamede, Asha Dopplapudi, Svemir Rudić, Madhusudan Tyagi, Victoria Garcia Sakai, Luís A. E. Batista de Carvalho
Format: Article
Language:English
Published: MDPI AG 2020-01-01
Series:Molecules
Subjects:
palladium anticancer drug
dna
hydration water
neutron scattering techniques
raman
ftir
Online Access:https://www.mdpi.com/1420-3049/25/2/246

Internet

https://www.mdpi.com/1420-3049/25/2/246

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