MTHFR Genetic Polymorphism As a Risk Factor in Egyptian Mothers with Down Syndrome Children

Recent reports linking Down syndrome (DS) to maternal polymorphisms at the methylenetetrahydrofolate reductase (MTHFR) gene locus have generated great interest among investigators in the field. The present study aimed at evaluation of MTHFR 677C/T and 1298A/C polymorphisms in the MTHFR gene as mater...

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Bibliographic Details
Main Authors: Nagwa A. Meguid, Ahmed A. Dardir, Mohamed Khass, Lamia El Hossieny, Afaf Ezzat, Mostafa K. El Awady
Format: Article
Language:English
Published: Hindawi Limited 2008-01-01
Series:Disease Markers
Online Access:http://dx.doi.org/10.1155/2008/214027

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