A novel chemical inhibitor suppresses breast cancer cell growth and metastasis through inhibiting HPIP oncoprotein

A novel chemical inhibitor suppresses breast cancer cell growth and metastasis through inhibiting HPIP oncoprotein

Abstract Increasing evidence suggests the pivotal role of hematopoietic pre-B-cell leukemia transcription factor (PBX)-interacting protein (HPIP/PBXIP1) in cancer development and progression, indicating that HPIP inhibition may be a promising target for cancer therapy. Here, we screened compounds in...

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Bibliographic Details
Main Authors: Pengyun Li, Shengjie Cao, Yubing Huang, Yanan Zhang, Jie Liu, Xu Cai, Lulu Zhou, Jianbin Li, Zefei Jiang, Lihua Ding, Zhibing Zheng, Song Li, Qinong Ye
Format: Article
Language:English
Published: Nature Publishing Group 2021-07-01
Series:Cell Death Discovery
Online Access:https://doi.org/10.1038/s41420-021-00580-3

Internet

https://doi.org/10.1038/s41420-021-00580-3

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