Reactive oxygen species drive herpes simplex virus (HSV)-1-induced proinflammatory cytokine production by murine microglia
<p>Abstract</p> <p>Background</p> <p>Production of reactive oxygen species (ROS) and proinflammatory cytokines by microglial cells in response to viral brain infection contributes to both pathogen clearance and neuronal damage. In the present study, we examined the effe...
Main Authors: | Lokensgard James R, Schachtele Scott J, Sheng Wen S, Hu Shuxian |
---|---|
Format: | Article |
Language: | English |
Published: |
BMC
2011-09-01
|
Series: | Journal of Neuroinflammation |
Online Access: | http://www.jneuroinflammation.com/content/8/1/123 |
Similar Items
-
Toll-like receptor 2 signaling is a mediator of apoptosis in herpes simplex virus-infected microglia
by: Lokensgard James R, et al.
Published: (2007-04-01) -
Herpes simplex virus induces neural oxidative damage via microglial cell Toll-like receptor-2
by: Little Morgan R, et al.
Published: (2010-06-01) -
Modulation of experimental herpes encephalitis-associated neurotoxicity through sulforaphane treatment.
by: Scott J Schachtele, et al.
Published: (2012-01-01) -
Reactivation of Herpes Simplex Virus (HSV) from Latency in Response to Neuronal Hyperexcitability
by: Sean Cuddy, et al.
Published: (2020-06-01) -
The epidemiology and natural history of genital herpes simplex virus (HSV) infection
by: Ramaswamy, Meghna
Published: (2006)