Reactive oxygen species drive herpes simplex virus (HSV)-1-induced proinflammatory cytokine production by murine microglia

<p>Abstract</p> <p>Background</p> <p>Production of reactive oxygen species (ROS) and proinflammatory cytokines by microglial cells in response to viral brain infection contributes to both pathogen clearance and neuronal damage. In the present study, we examined the effe...

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Bibliographic Details
Main Authors: Lokensgard James R, Schachtele Scott J, Sheng Wen S, Hu Shuxian
Format: Article
Language:English
Published: BMC 2011-09-01
Series:Journal of Neuroinflammation
Online Access:http://www.jneuroinflammation.com/content/8/1/123