Synthesis and antiproliferative activity of 4H-chromonephenylhydrazones, 1H-pyrazolecarboxylates and pyrazolylmethanones

Synthesis and antiproliferative activity of 4H-chromonephenylhydrazones, 1H-pyrazolecarboxylates and pyrazolylmethanones

Series of 4H-chromone-based hydrazones 3a–z, pyrazolecarboxylates 5a–x and pyrazolylmethanones 6a–u were prepared and screened for their anti-proliferative activity on A549, HeLa, DU145 and MDAMB 231 cell lines. The hydrazone compound 3s with a chloro substituent on the chromanone moiety and a metho...

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Bibliographic Details
Main Authors: China Raju Bhimapaka, Nageswara Rao Rayala, Rajkumar Kommera, Dayakar Cherupally, Ramalinga Murthy Thampunuri, V Kalivendi Shasi
Format: Article
Language:English
Published: Slovenian Chemical Society 2018-03-01
Series:Acta Chimica Slovenica
Subjects:
3-Formylchromones
1H-pyrazolecarboxylates
1H-pyrazolylmethanones
cycloaddition and antiproliferative activity
Online Access:https://journals.matheo.si/index.php/ACSi/article/view/3453

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