DNA damage repair in ovarian cancer: unlocking the heterogeneity

DNA damage repair in ovarian cancer: unlocking the heterogeneity

Abstract Treatment for advanced ovarian cancer is rarely curative; three quarters of patients with advanced disease relapse and ultimately die with resistant disease. Improving patient outcomes will require the introduction of new treatments and better patient selection. Abrogations in the DNA damag...

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Bibliographic Details
Main Authors: Mary Ellen Gee, Zahra Faraahi, Aiste McCormick, Richard J. Edmondson
Format: Article
Language:English
Published: BMC 2018-06-01
Series:Journal of Ovarian Research
Subjects:
Non-homologous end joining
Homologous recombination
Nucleotide excision repair
Base excision repair
Mismatch repair
Ovarian cancer
Online Access:http://link.springer.com/article/10.1186/s13048-018-0424-x

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http://link.springer.com/article/10.1186/s13048-018-0424-x

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