Myostatin gene targeting in cultured China Han ovine myoblast cells

Myostatin (MSTN), a member of the transforming growth factor-β superfamily, has been shown to be a negative regulator of myogenesis. Natural mutation in beef cattle causes double-muscling phenotypes. We report an investigation designed to knockout the MSTN gene by gene targeting in ovine myoblast ce...

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Bibliographic Details
Main Authors: L. Zhang, X. Yang, X. An, Y. Chen
Format: Article
Language:English
Published: Elsevier 2007-01-01
Series:Animal
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1751731107000717