Host immunity increases Mycobacterium tuberculosis reliance on cytochrome bd oxidase.
In order to sustain a persistent infection, Mycobacterium tuberculosis (Mtb) must adapt to a changing environment that is shaped by the developing immune response. This necessity to adapt is evident in the flexibility of many aspects of Mtb metabolism, including a respiratory chain that consists of...
Main Authors: | Yi Cai, Eleni Jaecklein, Jared S Mackenzie, Kadamba Papavinasasundaram, Andrew J Olive, Xinchun Chen, Adrie J C Steyn, Christopher M Sassetti |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2021-07-01
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Series: | PLoS Pathogens |
Online Access: | https://doi.org/10.1371/journal.ppat.1008911 |
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