Lead Exposure Induces Weight Gain in Adult Rats, Accompanied by DNA Hypermethylation.

Lead Exposure Induces Weight Gain in Adult Rats, Accompanied by DNA Hypermethylation.

Previous studies have revealed the association of lead (Pb) exposure with obesity. DNA methylation alteration has been suggested to be one of the regulatory mechanisms of obesity. We aimed to explore whether Pb exposure is related with weight gain and DNA methylation alteration.Male adult 8 week Wis...

Full description

Bibliographic Details
Main Authors:	Honglin Sun, Ningjian Wang, Xiaomin Nie, Li Zhao, Qin Li, Zhen Cang, Chi Chen, Meng Lu, Jing Cheng, Hualing Zhai, Fangzhen Xia, Lin Ye, Yingli Lu
Format:	Article
Language:	English
Published:	Public Library of Science (PLoS) 2017-01-01
Series:	PLoS ONE
Online Access:	http://europepmc.org/articles/PMC5249225?pdf=render

Similar Items

Modulation of Microbiota-Gut-Brain Axis by Berberine Resulting in Improved Metabolic Status in High-Fat Diet-Fed Rats
by: Honglin Sun, et al.
Published: (2016-11-01)

Blood lead level is associated with non-alcoholic fatty liver disease in the Yangtze River Delta region of China in the context of rapid urbanization
by: Hualing Zhai, et al.
Published: (2017-08-01)

Cadmium exposure and its association with serum uric acid and hyperuricemia
by: Honglin Sun, et al.
Published: (2017-04-01)

Association of 25-hydroxyvitamin D with cardiometabolic risk factors and metabolic syndrome: a mendelian randomization study
by: Chi Chen, et al.
Published: (2019-10-01)

Testosterone: Relationships with Metabolic Disorders in Men—An Observational Study from SPECT-China
by: Jing Cheng, et al.
Published: (2017-01-01)

Health-related quality of life in type-2 diabetes patients: a cross-sectional study in East China
by: You Lu, et al.
Published: (2017-07-01)

Serum Uric Acid Is Associated with Erectile Dysfunction: A Population-Based Cross-Sectional Study in Chinese Men
by: Fengbin Gao, et al.
Published: (2017-05-01)

Iodine nutrition status and its association with microvascular complications in urban dwellers with type 2 diabetes
by: Chi Chen, et al.
Published: (2020-08-01)

A Glucagon-Like Peptide-1 Receptor Agonist Lowers Weight by Modulating the Structure of Gut Microbiota
by: Li Zhao, et al.
Published: (2018-05-01)

Tracing Fasting Glucose Fluxes with Unstressed Catheter Approach in Streptozotocin Induced Diabetic Rats
by: Shichun Du, et al.
Published: (2014-01-01)

Sexual Dimorphism for the Association between Vitamin D and Insulin Resistance in Chinese People
by: Bing Han, et al.
Published: (2018-01-01)

Promoter DNA hypermethylation leads to Reelindown regulation in cancer cells
by: GUO-YU, LI, et al.
Published: (2012)

Low Sex Hormone-Binding Globulin Levels Associate with Prediabetes in Chinese Men Independent of Total Testosterone.
by: Hui Zhu, et al.
Published: (2016-01-01)

Vitamin D and Nonalcoholic Fatty Liver Disease: Bi-directional Mendelian Randomization Analysis
by: Ningjian Wang, et al.
Published: (2018-02-01)

Hypermethylation of Auxin-Responsive Motifs in the Promoters of the Transcription Factor Genes Accompanies the Somatic Embryogenesis Induction in Arabidopsis
by: Daria Grzybkowska, et al.
Published: (2020-09-01)

Comparison of the Prevalence of Metabolic Disease Between Two Types of Urbanization in China
by: Bing Han, et al.
Published: (2018-11-01)

LH/FSH Ratio Is Associated With Visceral Adipose Dysfunction in Chinese Women Older Than 55
by: Li Zhao, et al.
Published: (2018-08-01)

Hypermethylation of WNT3A gene and non-syndromic cleft lip and/or palate in association with in utero exposure to lead: A mediation analysis
by: Wenlei Yang, et al.
Published: (2021-01-01)

The Association of Thyroid Nodules with Metabolic Status: A Cross-Sectional SPECT-China Study
by: Yi Chen, et al.
Published: (2018-01-01)

Neck circumference as an independent indicator of visceral obesity in a Chinese population
by: Li Zhao, et al.
Published: (2018-04-01)

Hypermethylation leads to bone morphogenetic protein 6 downregulation in hepatocellular carcinoma.
by: Yinghua He, et al.
Published: (2014-01-01)

Association between serum vitamin D and uric acid in the eastern Chinese population: a population-based cross-sectional study
by: Yingchao Chen, et al.
Published: (2020-06-01)

Associations between the Neutrophil-to-Lymphocyte Ratio and Diabetic Complications in Adults with Diabetes: A Cross-Sectional Study
by: Heng Wan, et al.
Published: (2020-01-01)

Are Thyroid Autoimmune Diseases Associated with Cardiometabolic Risks in a Population with Normal Thyroid-Stimulating Hormone?
by: Yi Chen, et al.
Published: (2018-01-01)

Visceral adiposity and renal function: an observational study from SPECT-China
by: Kun Zhang, et al.
Published: (2017-10-01)

Association Between Thyroid-Stimulating Hormone and Renal Function: a Mendelian Randomization Study
by: Chi Chen, et al.
Published: (2018-07-01)

Calcium sensing receptor silencing in primary hyperparathyroidism associated with promoter hypermethylation and gain of methylation on histone 3
by: Priyanka Singh, et al.
Published: (2020-10-01)

Vitamin D is associated with blood lead exposure through bone turnover in type 2 diabetes patients
by: Haojie Zhang, et al.
Published: (2021-04-01)

Hypermethylation of SOX2 Promoter in Endometrial Carcinogenesis
by: Oscar Gee-Wan Wong, et al.
Published: (2010-01-01)

Age and gender-specific distribution of metabolic syndrome components in East China: role of hypertriglyceridemia in the SPECT-China study
by: Boren Jiang, et al.
Published: (2018-04-01)

The GLP-1 Analogue Exenatide Improves Hepatic and Muscle Insulin Sensitivity in Diabetic Rats: Tracer Studies in the Basal State and during Hyperinsulinemic-Euglycemic Clamp
by: Hui Wu, et al.
Published: (2014-01-01)

Study on aberrant DNA hypermethylation in HNSCC
by: Wei-Li Huang, et al.
Published: (2009)

Novel associations between sex hormones and diabetic vascular complications in men and postmenopausal women: a cross-sectional study
by: Chiyu Wang, et al.
Published: (2019-07-01)

The Associations Between Gonadal Hormones and Serum Uric Acid Levels in Men and Postmenopausal Women With Diabetes
by: Heng Wan, et al.
Published: (2020-02-01)

Influence of Rapid Urbanization on Thyroid Autoimmune Disease in China
by: Yingchao Chen, et al.
Published: (2021-01-01)

High-level dietary cadmium exposure is associated with global DNA hypermethylation in the gastropod hepatopancreas.
by: Dragos V Nica, et al.
Published: (2017-01-01)

Urinary Biomarkers of Phthalates Exposure, Blood Lead Levels, and Risks of Thyroid Nodules
by: Jingsi Chen, et al.
Published: (2021-03-01)

Serum alanine aminotransferase/aspartate aminotransferase ratio is one of the best markers of insulin resistance in the Chinese population
by: Li Zhao, et al.
Published: (2017-10-01)

A male-specific association between AGTR1 hypermethylation and coronary heart disease
by: Xiaojing Li, et al.
Published: (2019-09-01)

Discovery and Validation of Hypermethylated Markers for Colorectal Cancer
by: Jiufeng Wei, et al.
Published: (2016-01-01)

Cannot write session to /tmp/vufind_sessions/sess_0jbue53u24mhoff65uuaood2mv