Biodegradable and Dual‐Responsive Polypeptide‐Shelled Cyclodextrin‐Containers for Intracellular Delivery of Membrane‐Impermeable Cargo

Biodegradable and Dual‐Responsive Polypeptide‐Shelled Cyclodextrin‐Containers for Intracellular Delivery of Membrane‐Impermeable Cargo

Abstract The transport of membrane impermeable compounds into cells is a prerequisite for the efficient cellular delivery of hydrophilic and amphiphilic compounds and drugs. Transport into the cell's cytosolic compartment should ideally be controllable and it should involve biologically compati...

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Bibliographic Details
Main Authors: Sergej Kudruk, Sharafudheen Pottanam Chali, Anna Livia Linard Matos, Cole Bourque, Clara Dunker, Christos Gatsogiannis, Bart Jan Ravoo, Volker Gerke
Format: Article
Language:English
Published: Wiley 2021-09-01
Series:Advanced Science
Subjects:
biodegradable
cyclodextrin
dual‐responsive
intracellular delivery
polypeptides
Online Access:https://doi.org/10.1002/advs.202100694

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