MicroRNA-7, synergizes with RORα, negatively controls the pathology of brain tissue inflammation

MicroRNA-7, synergizes with RORα, negatively controls the pathology of brain tissue inflammation

Abstract Background Accumulating evidence has documented that microRNA-7 (miR-7) plays an important role in the pathology of various diseases. However, the potential role of miR-7 in brain tissue inflammation (BTI) remains unclear. Methods We detected the expression of miR-7 in LPS-induced murine BT...

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Bibliographic Details
Main Authors: Dongxu Yue, Juanjuan Zhao, Huizi Chen, Mengmeng Guo, Chao Chen, Ya Zhou, Lin Xu
Format: Article
Language:English
Published: BMC 2020-01-01
Series:Journal of Neuroinflammation
Subjects:
miR-7
Brain tissue inflammation
Neuron
NF-κB
RORα
RNA interference
Online Access:https://doi.org/10.1186/s12974-020-1710-2

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