Study the voltammetric behavior of 10-Hydroxycamptothecin and its sensitive determination at electrochemically reduced graphene oxide modified glassy carbon electrode
The electrochemical properties of 10-Hydroxycamptothecin were investigated systematically at a reduced graphene oxide modified glassy carbon electrode. A new pair of redox peaks of 10-Hydroxycamptothecin was reported for the first time with quasi-reversible process driven by adsorption. The dynamics...
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doaj-7899a8975216454287e047df3836377c2020-11-25T03:30:34ZengElsevierArabian Journal of Chemistry1878-53522019-12-0112827322739Study the voltammetric behavior of 10-Hydroxycamptothecin and its sensitive determination at electrochemically reduced graphene oxide modified glassy carbon electrodeKunjing Li0Yinfeng Li1Lu Wang2Lingxi Yang3Baoxian Ye4College of Chemistry and Molecular Engineering, Zhengzhou University, Zhengzhou 450001, PR ChinaCollege of Chemistry and Molecular Engineering, Zhengzhou University, Zhengzhou 450001, PR China; School of Chemical and Material Engineering, Henan University of Urban Construction, Pingdingshan 467036, PR ChinaCollege of Chemistry and Molecular Engineering, Zhengzhou University, Zhengzhou 450001, PR China; Department of Environmental Engineering and Chemistry, Luoyang Institute of Science and Technology, Luoyang 471023, PR ChinaCollege of Chemistry and Molecular Engineering, Zhengzhou University, Zhengzhou 450001, PR ChinaCollege of Chemistry and Molecular Engineering, Zhengzhou University, Zhengzhou 450001, PR China; Corresponding author. Tel.: +86 0371 67781757; fax: +86 0371 67763654.The electrochemical properties of 10-Hydroxycamptothecin were investigated systematically at a reduced graphene oxide modified glassy carbon electrode. A new pair of redox peaks of 10-Hydroxycamptothecin was reported for the first time with quasi-reversible process driven by adsorption. The dynamics parameters of electrode process were calculated using various electrochemical techniques. Owing to the large surface area, good conductivity of electrochemically reduced graphene oxide, the sensor exhibited sensitive activity for 10-Hydroxycamptothecin, displaying a wide linear response from 1.5 × 10−8 mol L−1 to 5.0 × 10−7 mol L−1 and 5.0 × 10−7 mol L−1 to 3.0 × 10−6 mol L−1 (Fig. 8). A simple, sensitive and new voltammetric method for the determination of 10-Hydroxycamptothecin was proposed with a determination limit of 1.5 × 10−8 mol L−1 and recoveries were determined in the range of 94.2–104%. Keywords: 10-Hydroxycamptothecin, Electrochemically reduced graphene oxide, Determination, Electrochemical propertieshttp://www.sciencedirect.com/science/article/pii/S1878535215001628 |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Kunjing Li Yinfeng Li Lu Wang Lingxi Yang Baoxian Ye |
spellingShingle |
Kunjing Li Yinfeng Li Lu Wang Lingxi Yang Baoxian Ye Study the voltammetric behavior of 10-Hydroxycamptothecin and its sensitive determination at electrochemically reduced graphene oxide modified glassy carbon electrode Arabian Journal of Chemistry |
author_facet |
Kunjing Li Yinfeng Li Lu Wang Lingxi Yang Baoxian Ye |
author_sort |
Kunjing Li |
title |
Study the voltammetric behavior of 10-Hydroxycamptothecin and its sensitive determination at electrochemically reduced graphene oxide modified glassy carbon electrode |
title_short |
Study the voltammetric behavior of 10-Hydroxycamptothecin and its sensitive determination at electrochemically reduced graphene oxide modified glassy carbon electrode |
title_full |
Study the voltammetric behavior of 10-Hydroxycamptothecin and its sensitive determination at electrochemically reduced graphene oxide modified glassy carbon electrode |
title_fullStr |
Study the voltammetric behavior of 10-Hydroxycamptothecin and its sensitive determination at electrochemically reduced graphene oxide modified glassy carbon electrode |
title_full_unstemmed |
Study the voltammetric behavior of 10-Hydroxycamptothecin and its sensitive determination at electrochemically reduced graphene oxide modified glassy carbon electrode |
title_sort |
study the voltammetric behavior of 10-hydroxycamptothecin and its sensitive determination at electrochemically reduced graphene oxide modified glassy carbon electrode |
publisher |
Elsevier |
series |
Arabian Journal of Chemistry |
issn |
1878-5352 |
publishDate |
2019-12-01 |
description |
The electrochemical properties of 10-Hydroxycamptothecin were investigated systematically at a reduced graphene oxide modified glassy carbon electrode. A new pair of redox peaks of 10-Hydroxycamptothecin was reported for the first time with quasi-reversible process driven by adsorption. The dynamics parameters of electrode process were calculated using various electrochemical techniques. Owing to the large surface area, good conductivity of electrochemically reduced graphene oxide, the sensor exhibited sensitive activity for 10-Hydroxycamptothecin, displaying a wide linear response from 1.5 × 10−8 mol L−1 to 5.0 × 10−7 mol L−1 and 5.0 × 10−7 mol L−1 to 3.0 × 10−6 mol L−1 (Fig. 8). A simple, sensitive and new voltammetric method for the determination of 10-Hydroxycamptothecin was proposed with a determination limit of 1.5 × 10−8 mol L−1 and recoveries were determined in the range of 94.2–104%. Keywords: 10-Hydroxycamptothecin, Electrochemically reduced graphene oxide, Determination, Electrochemical properties |
url |
http://www.sciencedirect.com/science/article/pii/S1878535215001628 |
work_keys_str_mv |
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