Study the voltammetric behavior of 10-Hydroxycamptothecin and its sensitive determination at electrochemically reduced graphene oxide modified glassy carbon electrode

The electrochemical properties of 10-Hydroxycamptothecin were investigated systematically at a reduced graphene oxide modified glassy carbon electrode. A new pair of redox peaks of 10-Hydroxycamptothecin was reported for the first time with quasi-reversible process driven by adsorption. The dynamics...

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Main Authors: Kunjing Li, Yinfeng Li, Lu Wang, Lingxi Yang, Baoxian Ye
Format: Article
Language:English
Published: Elsevier 2019-12-01
Series:Arabian Journal of Chemistry
Online Access:http://www.sciencedirect.com/science/article/pii/S1878535215001628
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spelling doaj-7899a8975216454287e047df3836377c2020-11-25T03:30:34ZengElsevierArabian Journal of Chemistry1878-53522019-12-0112827322739Study the voltammetric behavior of 10-Hydroxycamptothecin and its sensitive determination at electrochemically reduced graphene oxide modified glassy carbon electrodeKunjing Li0Yinfeng Li1Lu Wang2Lingxi Yang3Baoxian Ye4College of Chemistry and Molecular Engineering, Zhengzhou University, Zhengzhou 450001, PR ChinaCollege of Chemistry and Molecular Engineering, Zhengzhou University, Zhengzhou 450001, PR China; School of Chemical and Material Engineering, Henan University of Urban Construction, Pingdingshan 467036, PR ChinaCollege of Chemistry and Molecular Engineering, Zhengzhou University, Zhengzhou 450001, PR China; Department of Environmental Engineering and Chemistry, Luoyang Institute of Science and Technology, Luoyang 471023, PR ChinaCollege of Chemistry and Molecular Engineering, Zhengzhou University, Zhengzhou 450001, PR ChinaCollege of Chemistry and Molecular Engineering, Zhengzhou University, Zhengzhou 450001, PR China; Corresponding author. Tel.: +86 0371 67781757; fax: +86 0371 67763654.The electrochemical properties of 10-Hydroxycamptothecin were investigated systematically at a reduced graphene oxide modified glassy carbon electrode. A new pair of redox peaks of 10-Hydroxycamptothecin was reported for the first time with quasi-reversible process driven by adsorption. The dynamics parameters of electrode process were calculated using various electrochemical techniques. Owing to the large surface area, good conductivity of electrochemically reduced graphene oxide, the sensor exhibited sensitive activity for 10-Hydroxycamptothecin, displaying a wide linear response from 1.5 × 10−8 mol L−1 to 5.0 × 10−7 mol L−1 and 5.0 × 10−7 mol L−1 to 3.0 × 10−6 mol L−1 (Fig. 8). A simple, sensitive and new voltammetric method for the determination of 10-Hydroxycamptothecin was proposed with a determination limit of 1.5 × 10−8 mol L−1 and recoveries were determined in the range of 94.2–104%. Keywords: 10-Hydroxycamptothecin, Electrochemically reduced graphene oxide, Determination, Electrochemical propertieshttp://www.sciencedirect.com/science/article/pii/S1878535215001628
collection DOAJ
language English
format Article
sources DOAJ
author Kunjing Li
Yinfeng Li
Lu Wang
Lingxi Yang
Baoxian Ye
spellingShingle Kunjing Li
Yinfeng Li
Lu Wang
Lingxi Yang
Baoxian Ye
Study the voltammetric behavior of 10-Hydroxycamptothecin and its sensitive determination at electrochemically reduced graphene oxide modified glassy carbon electrode
Arabian Journal of Chemistry
author_facet Kunjing Li
Yinfeng Li
Lu Wang
Lingxi Yang
Baoxian Ye
author_sort Kunjing Li
title Study the voltammetric behavior of 10-Hydroxycamptothecin and its sensitive determination at electrochemically reduced graphene oxide modified glassy carbon electrode
title_short Study the voltammetric behavior of 10-Hydroxycamptothecin and its sensitive determination at electrochemically reduced graphene oxide modified glassy carbon electrode
title_full Study the voltammetric behavior of 10-Hydroxycamptothecin and its sensitive determination at electrochemically reduced graphene oxide modified glassy carbon electrode
title_fullStr Study the voltammetric behavior of 10-Hydroxycamptothecin and its sensitive determination at electrochemically reduced graphene oxide modified glassy carbon electrode
title_full_unstemmed Study the voltammetric behavior of 10-Hydroxycamptothecin and its sensitive determination at electrochemically reduced graphene oxide modified glassy carbon electrode
title_sort study the voltammetric behavior of 10-hydroxycamptothecin and its sensitive determination at electrochemically reduced graphene oxide modified glassy carbon electrode
publisher Elsevier
series Arabian Journal of Chemistry
issn 1878-5352
publishDate 2019-12-01
description The electrochemical properties of 10-Hydroxycamptothecin were investigated systematically at a reduced graphene oxide modified glassy carbon electrode. A new pair of redox peaks of 10-Hydroxycamptothecin was reported for the first time with quasi-reversible process driven by adsorption. The dynamics parameters of electrode process were calculated using various electrochemical techniques. Owing to the large surface area, good conductivity of electrochemically reduced graphene oxide, the sensor exhibited sensitive activity for 10-Hydroxycamptothecin, displaying a wide linear response from 1.5 × 10−8 mol L−1 to 5.0 × 10−7 mol L−1 and 5.0 × 10−7 mol L−1 to 3.0 × 10−6 mol L−1 (Fig. 8). A simple, sensitive and new voltammetric method for the determination of 10-Hydroxycamptothecin was proposed with a determination limit of 1.5 × 10−8 mol L−1 and recoveries were determined in the range of 94.2–104%. Keywords: 10-Hydroxycamptothecin, Electrochemically reduced graphene oxide, Determination, Electrochemical properties
url http://www.sciencedirect.com/science/article/pii/S1878535215001628
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