Kinesin-2 and IFT-A act as a complex promoting nuclear localization of β-catenin during Wnt signalling
IFT-A proteins and Kinesin-2 modulate canonical Wnt/Wg-signalling independent of their ciliary role, but how is unclear. Here, the authors show that Kinesin-2 and IFT-A act as a complex to promote nuclear translocation of β-catenin in Drosophila and mouse MEF Wnt signalling independent of its ciliar...
Main Authors: | Linh T. Vuong, Carlo Iomini, Sophie Balmer, Davide Esposito, Stuart A. Aaronson, Marek Mlodzik |
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2018-12-01
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Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/s41467-018-07605-z |
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