Potential role of IL-17-producing iNKT cells in type 1 diabetes.

We explored in this study the status and potential role of IL-17-producing iNKT cells (iNKT17) in type 1 diabetes (T1D) by analyzing these cells in patients with T1D, and in NOD mice, a mouse model for T1D. Our analysis in mice showed an increase of iNKT17 cells in NOD vs control C57BL/6 mice, partl...

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Bibliographic Details
Main Authors: Shamin Li, Claudine Joseph, Chantal Becourt, Jihene Klibi, Sandrine Luce, Daniele Dubois-Laforgue, Etienne Larger, Christian Boitard, Kamel Benlagha
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4005752?pdf=render