Multiple Facets of cAMP Signalling and Physiological Impact: cAMP Compartmentalization in the Lung

Multiple Facets of cAMP Signalling and Physiological Impact: cAMP Compartmentalization in the Lung

Therapies involving elevation of the endogenous suppressor cyclic AMP (cAMP) are currently used in the treatment of several chronic inflammatory disorders, including chronic obstructive pulmonary disease (COPD). Characteristics of COPD are airway obstruction, airway inflammation and airway remodelli...

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Bibliographic Details
Main Authors: Martina Schmidt, Harm Maarsingh, Anouk Oldenburger
Format: Article
Language:English
Published: MDPI AG 2012-11-01
Series:Pharmaceuticals
Subjects:
cAMP compartmentalization
barrier function
COPD
A-kinase anchoring proteins (AKAPs)
Epac
Online Access:http://www.mdpi.com/1424-8247/5/12/1291

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