Context-aware seeds for read mapping
Abstract Motivation Most modern seed-and-extend NGS read mappers employ a seeding scheme that requires extracting t non-overlapping seeds in each read in order to find all valid mappings under an edit distance threshold of t. As t grows, this seeding scheme forces mappers to use more and shorter see...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
BMC
2020-05-01
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| Series: | Algorithms for Molecular Biology |
| Subjects: | |
| Online Access: | http://link.springer.com/article/10.1186/s13015-020-00172-3 |