<it>Legionella pneumophila </it>induces cathepsin B-dependent necrotic cell death with releasing high mobility group box1 in macrophages

<it>Legionella pneumophila </it>induces cathepsin B-dependent necrotic cell death with releasing high mobility group box1 in macrophages

<p>Abstract</p> <p>Background</p> <p><it>Legionella pneumophila </it>(LPN) can cause a lethal infectious disease with a marked inflammatory response in humans. However, the mechanism of this severe inflammation remains poorly understood. Since necrosis is kn...

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Main Authors: Kakeya Hiroshi, Izumikawa Koichi, Seki Masafumi, Hasegawa Hiroo, Nakamura Shigeki, Yanagihara Katsunori, Morinaga Yoshitomo, Yamamoto Yoshihiro, Yamada Yasuaki, Kohno Shigeru, Kamihira Shimeru
Format: Article
Language:English
Published: BMC 2010-11-01
Series:Respiratory Research
Online Access:http://respiratory-research.com/content/11/1/158

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