Increased H+ efflux is sufficient to induce dysplasia and necessary for viability with oncogene expression
Intracellular pH (pHi) dynamics is increasingly recognized as an important regulator of a range of normal and pathological cell behaviors. Notably, increased pHi is now acknowledged as a conserved characteristic of cancers and in cell models is confirmed to increase proliferation and migration as we...
Main Authors: | Bree K Grillo-Hill, Changhoon Choi, Maite Jimenez-Vidal, Diane L Barber |
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Format: | Article |
Language: | English |
Published: |
eLife Sciences Publications Ltd
2015-03-01
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Series: | eLife |
Subjects: | |
Online Access: | https://elifesciences.org/articles/03270 |
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