Neutrophil arrest by LFA-1 activation

Neutrophil arrest by LFA-1 activation

Lymphocyte function-associated antigen-1 (LFA-1) is a heterodimeric integrin consisiting of αL (gene name, Itgal) and β2 (gene name, Itgb2) subunits expressed in all leukocytes. LFA-1 is essential for neutrophil recruitment to inflamed tissue. Activation of LFA-1 by chemokines allows neutrophils and...

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Bibliographic Details
Main Authors:	Craig T. Lefort, Klaus eLey
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2012-06-01
Series:	Frontiers in Immunology
Subjects:	Inflammation chemokine Neutrophil integrin LFA-1
Online Access:	http://journal.frontiersin.org/Journal/10.3389/fimmu.2012.00157/full

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